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Tests for risky plasticisers in antibiotics to improve safety

Published: Monday, July 25, 2011

Representatives of authorised agencies conduct an inspection at a pharmaceutical distributor on Ha Noi City's Ngoc Khanh Street. — VNA/VNS Photo Thanh Tung

Representatives of authorised agencies conduct an inspection at a pharmaceutical distributor on Ha Noi City's Ngoc Khanh Street. — VNA/VNS Photo Thanh Tung

HA NOI — Drug Administration of Viet Nam Director Truong Quoc Cuong has called on the Central Drug Testing and HCM City Drug Testing institutes to test Augmentin-containing products, commonly used as an antibiotic for bacterial infections, in Viet Nam.

Augmentin syrup (156mg/5ml and 457mg/5ml) was found to contain the plasticisers Diisodecyl Phthalate (DIDP) and Diisononyl Phthalate (DINP) in Hong Kong last month.

Testing is aimed at determining the levels of DIDP, Di-ethylh Exyl Phthalates (DEHP) and other derivatives present in the antibiotic.

According to the Hong Kong Department of Health (HKDH), data gathered via animal studies suggests that long-term, high-level consumption of DIDP might affect the liver.

Based on their findings, and while the HKDH urged GlaxoSmithKline Limited (GSK) to immediately recall Augmentin 375mg tablets from shelves, the levels of plasticisers are considered unlikely to cause acute harmful effects if taken according to the recommended dosage.

According to Cuong, registration for Augmentin tablets (375mg) issued in Viet Nam expired in 2001. The GSK still did not re-register at the ministry, he said.

To ensure user safety, health departments have been called upon to inform health clinics and medicine producers regarding information related to the Augmentin antibiotic.

In addition, the GSK, urged to co-operate in efforts to minimise and research the harmful effects of the drug, has been asked to provide information on material, packaging and production to the administration before August 5. — VNS

Tags for Tests for risky plasticisers in antibiotics to improve safety:  AugmentinplasticisersDrugDrug TestingHong KongAugmentin tabletsharmful effects
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